NBQX attenuates relapse of nicotine seeking but not nicotine and methamphetamine self-administration in rats

Warning

This publication doesn't include Faculty of Economics and Administration. It includes Faculty of Medicine. Official publication website can be found on muni.cz.
Authors

RUDÁ Jana AMCHOVÁ Petra ŠIŠKA Filip TIZABI Yousef

Year of publication 2021
Type Article in Periodical
Magazine / Source The World Journal of Biological Psychiatry
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.tandfonline.com/doi/full/10.1080/15622975.2021.1907714
Doi http://dx.doi.org/10.1080/15622975.2021.1907714
Keywords AMPA/kainate receptor; Nicotine; Methamphetamine; Self-administration; Relapse
Description Pharmacological manipulations of glutamatergic ionotropic receptors have been suggested as a promising target for addiction treatment. Antagonists of AMPA/kainate receptors were shown to reduce alcohol intake or alcohol-seeking in various animal models. In this study, we evaluated the effect of NBQX, an AMPA/kainate receptor antagonist, on methamphetamine (METH) and nicotine self-administration in rats.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.