Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs

Hanáková,  Kateřina; Bernatík,  Ondřej; Kravec,  Marek; Micka,  Miroslav; Kumar,  Jitender; Harnoš,  Jakub; Ovesná,  Petra; Paclíková,  Petra; Rádsetoulal,  Matěj; Potěšil,  David; Tripsianes,  Konstantinos; Čajánek,  Lukáš; Zdráhal,  Zbyněk; Bryja,  Vítězslav

Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs

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Authors	HANÁKOVÁ Kateřina BERNATÍK Ondřej KRAVEC Marek MICKA Miroslav KUMAR Jitender HARNOŠ Jakub OVESNÁ Petra PACLÍKOVÁ Petra RÁDSETOULAL Matěj POTĚŠIL David TRIPSIANES Konstantinos ČAJÁNEK Lukáš ZDRÁHAL Zbyněk BRYJA Vítězslav
Year of publication	2019
Type	Article in Periodical
Magazine / Source	Cell Communication and Signaling
MU Faculty or unit	Faculty of Science
Citation
Web	https://biosignaling.biomedcentral.com/articles/10.1186/s12964-019-0470-z
Doi	http://dx.doi.org/10.1186/s12964-019-0470-z
Keywords	CK1; Dishevelled; DVL3; Kinase; Mass spectrometry; NEK2; Phosphorylation; TTBK2; Wnt
Description	Dishevelled (DVL) is an essential component of the Wnt signaling cascades. Function of DVL is controlled by phosphorylation but the molecular details are missing. DVL3 contains 131 serines and threonines whose phosphorylation generates complex barcodes underlying diverse DVL3 functions.
Related projects:	Tau tubulin kináza 2 v ciliogenezi: molekularní mechanismy a funkční důsledky CEITEC 2020 Odhalení tajemství signální dráhy WNT analýzou struktury proteinu Dishevelled Molekulární a funkční analýza biologie kasein kinázy 1 Molekulární aspekty ciliogeneze: zaměření na Tau Tubulin Kinázu 2