Looking for inhibitor: structural and functional analysis of novel bangle lectin PHL from Photorhabdus asymbiotica
| Authors | |
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| Year of publication | 2018 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | In Photorhabdus asymbiotica genom, we identified a gene for a putative lectin, and examined the corresponding recombinant protein PHL from functional and structural point of view. We succeeded in determining structure of PHL in complex with several monosaccharides and tested a wide range of various mono-, di- and oligovalent carbohydrate-based molecules. Data gained so far show the way for design and synthesis of potential therapeutics. |
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