Myasthenia Gravis Composite - validace české verze
| Title in English | Myasthenia Gravis Composite - Validation of the Czech Version |
|---|---|
| Authors | |
| Year of publication | 2016 |
| Type | Article in Periodical |
| Magazine / Source | Česká a slovenská neurologie a neurochirurgie |
| MU Faculty or unit | |
| Citation | |
| Field | Neurology, neurosurgery, neurosciences |
| Keywords | myasthenia; score; Quantitative Myasthenia Gravis |
| Description | Objective: In 2008, the new MG Composite score was constructed from selected items of existing scales of myasthenia (QMG, MMT-MG, MG-ADL). The aim of this study was to validate the Czech version of MGC and to check reliability of the new scale in a group of patients from the Neuromuscular Centre of the University Hospital in Brno. Methods: The Czech translation of MGC was validated by forward-backward translation. Inter-rater reliability was assessed with 40 patients (during a routine outpatient visit or hospitalization). Patients were assessed independently by two neurologists on the same day within 10-60 min (SV and MCH). Results: Intra-class correlation coefficient was 0.989 (CI = 0.98-0.994). Regression analysis of our data did not prove any systemic bias of difference according to MGC score (p = 0.616). Spearman correlation coefficient for the absolute difference in MGC value and the mean MGC of individual patients was 0.561. Conclusion: MG Composite is an effective tool for long-term monitoring of patients, evaluation of treatment effect and comparing data suitable for use in routine clinical practice. |
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