Myasthenia Gravis Composite - validace české verze

Warning

This publication doesn't include Faculty of Economics and Administration. It includes Faculty of Medicine. Official publication website can be found on muni.cz.
Title in English Myasthenia Gravis Composite - Validation of the Czech Version
Authors

CHMELÍKOVÁ Magda VOHÁŇKA Stanislav BEDNAŘÍK Josef

Year of publication 2016
Type Article in Periodical
Magazine / Source Česká a slovenská neurologie a neurochirurgie
MU Faculty or unit

Faculty of Medicine

Citation
Field Neurology, neurosurgery, neurosciences
Keywords myasthenia; score; Quantitative Myasthenia Gravis
Description Objective: In 2008, the new MG Composite score was constructed from selected items of existing scales of myasthenia (QMG, MMT-MG, MG-ADL). The aim of this study was to validate the Czech version of MGC and to check reliability of the new scale in a group of patients from the Neuromuscular Centre of the University Hospital in Brno. Methods: The Czech translation of MGC was validated by forward-backward translation. Inter-rater reliability was assessed with 40 patients (during a routine outpatient visit or hospitalization). Patients were assessed independently by two neurologists on the same day within 10-60 min (SV and MCH). Results: Intra-class correlation coefficient was 0.989 (CI = 0.98-0.994). Regression analysis of our data did not prove any systemic bias of difference according to MGC score (p = 0.616). Spearman correlation coefficient for the absolute difference in MGC value and the mean MGC of individual patients was 0.561. Conclusion: MG Composite is an effective tool for long-term monitoring of patients, evaluation of treatment effect and comparing data suitable for use in routine clinical practice.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.