Addenbrookský kognitivní test – orientační normy pro českou populaci

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Title in English Addenbrooke’s Cognitive Examination – Approximate Normal Values for the Czech Population
Authors

BERÁNKOVÁ Dagmar KRULOVÁ P. MRAČKOVÁ Martina ELIÁŠOVÁ Ilona KOŠŤÁLOVÁ Milena JANOUŠOVÁ Eva STEHNOVÁ Iva BAR M. RESSNER P. NILIUS P. TOMAGOVÁ M. REKTOROVÁ Irena

Year of publication 2015
Type Article in Periodical
Magazine / Source Česká a Slovenská neurologie a neurochirurgie
MU Faculty or unit

Faculty of Medicine

Citation
Field Neurology, neurosurgery, neurosciences
Keywords Addenbrooke's cognitive examination; normal values; cognitive deficit
Attached files
Description Aim: The aim of this study was to provide benchmark normal values for Addenbrooke’s cognitive examination (ACE-R) and its domains for the Czech population. Methods: The study included 143 healthy subjects (89 women and 54 men) aged 55–89 years, without brain injury, neurodegenerative disease, severe hearing or visual impairment and without a psychiatric disease, with MMSE above 27 points. Participants were interviewed in detail to ascertain any previous brain injury history and to determine the level of self-suffi ciency in daily living activities. Individuals with a history of brain injury or impaired self-suffi ciency were excluded from the study. ACE-R values and values for its domains in men and women were compared with Mann-Whitney test and values for the four age and education groups were compared using the Kruskal-Wallis test. P-values were corrected for multiple testing using Bonferroni correction. Results: Cut-off scores were set at 2nd and 7th percentile. Negative correlation with age (p < 0.001, r = –0.43) and positive correlation with education (p < 0.001, r = 0.41) were statistically signifi cant for the overall test performance and also for the performance in individual cognitive domains except for the Attention and orientation domain. The eff ect of sex was not statistically signifi cant. The cut-off score for the total score in Addenbrooke’s cognitive examination for all subjects aged 55–89 years is 74 points at the 2nd percentile and 79 points at the 7th percentile. Conclusion: The study suggests cut-off scores for the Czech population of ACE-R and provides the basis for the development of Czech norms for this test.
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