Raman tweezers on bacteria: Following the mechanisms of bacteriostatic versus bactericidal action
| Authors | |
|---|---|
| Year of publication | 2014 |
| Type | Article in Proceedings |
| Conference | Proceedings of SPIE : BIOPHOTONICS: PHOTONIC SOLUTIONS FOR BETTER HEALTH CARE IV |
| MU Faculty or unit | |
| Citation | |
| Doi | http://dx.doi.org/10.1117/12.2052538 |
| Field | Medical equipment |
| Keywords | optical trapping; tweezers; Raman spectroscopy; bacteria; antibiotics action |
| Description | Raman tweezers represents a unique method for identification of different microorganisms on the basis of Raman scattering. Raman tweezers allows us to fix and sterile manipulate with the trapped object and in the same time check the growth, viability, response to the external environment etc by Raman signal evaluating. The investigations presented here include distinction of bacteria in general(staphylococcal cells), identification of bacteria strains (biofilm-positive and biofilm-negative) by using principal component analysis (PCA) and monitoring the influence of antibiotics. |
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