Towards functional repertoire of the earliest proteins

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Authors	SOBOLEVSKY Y. GUIMARAES R. C TRIFONOV Eduard Nikolajevič
Year of publication	2013
Type	Article in Periodical
Magazine / Source	Journal of Biomolecular Structure & Dynamics
MU Faculty or unit	Central European Institute of Technology
Citation
Doi	http://dx.doi.org/10.1080/07391102.2012.735623
Field	Genetics and molecular biology
Keywords	ABC cassettes; protein modules; earliest proteins; omnipresent motifs; last universal cellular ancestor
Description	The conserved protein sequence motifs present in all prokaryotic proteomes, omnipresent motifs, presumably, correspond to the earliest proteins of the Last Universal Cellular Ancestor, from which all the proteomes have descended. Future analysis of less conserved sequence motifs may reveal at what degree of conservation (stage of evolution) the metabolic enzymes could have entered the scene.
Related projects:	Molecular basis of cell and tissue regulations