Extended paired dependences´ test

Investor logo

Warning

This publication doesn't include Faculty of Economics and Administration. It includes Faculty of Science. Official publication website can be found on muni.cz.
Authors

KNÍŽEK Jiří BERÁNEK Ladislav BOUCHAL Pavel VOJTĚŠEK Bořivoj NENUTIL Rudolf TOMŠÍK Pavel

Year of publication 2013
Type Article in Periodical
Magazine / Source International Journal of Applied Mathematics and Statistics
MU Faculty or unit

Faculty of Science

Citation
Web Web page
Field General mathematics
Keywords Decision making; Paired test of hypothesis; Biomarkers; Molecular biology; Markers
Description This paper deals with a special task following experimental practice in molecular biology. A special test construction was accomplished for this purpose. A test named Extended Paired Dependences’ Test can execute paired experiments in the following way. For the jth individual (a person, a patient, an animal, a microorganism etc.) experimental samples (dependences) in the number M_(j, diseased) are provided and simultaneously experimental samples in the number M_(j, healthy), where j = 1, 2, . . ., J. Generally, the numbers M_(j, diseased) and M_(j, healthy) need not be the same. Withal, symbol M_(j, diseased) represents number of samples obtained from, e.g., tumor tissue and M_(j, healthy) represents the number of samples obtained from healthy tissue at the same jth person. Symbol J represents the number of examined individuals (persons, patients, animals, microorganisms etc.). This test construction is relatively easily enabled with the help of the definition matrix approach. In practice, a need of the test can occur very often for miscellaneous reasons. E.g., some samples are not well done for experimental (anatomical, biochemical, etc.) reasons. Sometimes, a making of further samples can be financially too expensive or, simply, unworkable (e.g., for ethical reasons).
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.