New Laser Desorption Sample Introduction Techniques for Inductively Coupled Plasma Mass Spectrometry

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This publication doesn't include Faculty of Economics and Administration. It includes Central European Institute of Technology. Official publication website can be found on muni.cz.
Authors

PREISLER Jan FOLTYNOVÁ Pavla KANICKÝ Viktor TOMALOVÁ Iva VACULOVIČ Tomáš

Year of publication 2013
Type Conference abstract
MU Faculty or unit

Central European Institute of Technology

Citation
Description New techniques for determination of trace elements in submicroliter sample volumes, substrate-assisted laser desorption (SALD)1,2 and diode laser thermal vaporization (DLTV)3 inductively-coupled plasma mass spectrometry (ICP-MS) will be presented. In summary, the both SALD and DLTV ICP-MS are suitable for quantitative elemental analysis of low-volume samples (typically 100 – 500 nL) and represent an alternative to nebulizers. Ad-vantages are also easy archiving, transportation, prearrangement of calibration sets and high through-put due to minimization of memory effects. In addition, biological samples, such as metalloproteins or metal complexes can be analyzed in other detection modes (MALDI-MS or fluorescence) from the same sample, which can provide supplementary information, e.g. protein mass or identity.
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