Project information
Deciphering the fate and function of Notch1 positive mammary fibroblasts (NOTCHFIB)

Information

This project doesn't include Faculty of Economics and Administration. It includes Faculty of Medicine. Official project website can be found on muni.cz.
Project Identification
MUNI/IGA/1314/2021
Project Period
1/2022 - 12/2022
Investor / Pogramme / Project type
Masaryk University
MU Faculty or unit
Faculty of Medicine

Branching morphogenesis is an inter-species conserved mechanisms of functional organ development. Signals from mesenchyme/stroma are established as a crucial regulator of epithelial branching morphogenesis of many organs, including mammary gland (MG). However, regulation of stromal cell biology is not well studied. In this project, I will combine genetic tracing of Notch1 positive (Notch1+) fibroblast with single cell RNA sequencing to elucidate stromal hierarchy during mammary development.

Publications

Total number of publications: 1


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