Project information
Plasticity of Regulatory Mechanisms of the Central Nervous Systems
- Project Identification
- MSM141100001
- Project Period
- 1/1999 - 1/2004
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
- Faculty of Medicine
- Keywords
- Plasticity; Regulatory Mechanisms; Central Nervous System; Preclinical and Clinical Aspects; Neurobiology; Neurophysiology; Neuroanatomy; Neuropharmacology; Clinical Neurology; Psychiatry; Regeneration Processes; Neurotransmitters; Epilepsy
The central nervous system, its neurobiological mechanisms and the possibilities of influencing them externally have become the subject of the BRAIN DECADE in the research strategy announced by president Bush and enacted in the USA in 1990, to which Europe joined in 1992. The intentions included into the project being submitted, i.e. the investigation of the neurobiological and neurophysiological mechanisms of the control of the motor and mental functions, of their abnormalities, and the possible therapeutic or preventive influencing of these are completely in line with the "Brain Decade" programme. The project a based on an integration of the of pre-clinical aspects of the research in neuroanatomy, neurophysiology, pharmacology, and clinical research in the clinical fields of neurology, neurosurgery, plastic surgery and psychiatry. 16 postgraduate students have been included into this faculty research.
Publications
Total number of publications: 704
2000
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Cortical and subcortical distribution of sensory and cognitive operations. A contingent negative variation SEEG study
Clinical Neurophysiology, year: 2000, volume: 111, edition: Suppl.1
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Diferenciální diagnostika epileptických a neepileptických (pseudoepileptických) záchvatů v klinické praxi.
Neurologie pro praxi., year: 2000, volume: I, edition: 1
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DO ANTICONVULSANTS GABAPENTIN AND LAMOTRIGINE INDUCE IN MICE BEHAVIOURAL CHANGES SUGGESTING THEIR POTENTIAL ANTIDEPRESSANT ACTIVITY?
The International Journal of Neuropsychopharmacology, year: 2000, volume: ?, edition: 3(Suppl.1)
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EEG and motor responses to target stimuli in an oddball paradigm: SEEG recordings in epileptic patients.
Homeostasis, year: 2000, volume: 40, edition: 3-4
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Effect of vagal nerve stimulation on auditory and visual event-related potentials.
Epilepsia, year: 2000, volume: 41, edition: 1
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Effects of acute and repeated administration of caffeine in the mouse model of aggression and anxiety
European Journal of Neuroscience, year: 2000, volume: ?, edition: 12 Supp.1
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Effects of psychopharmacotherapy on phenotypic expression of cytochrome P450 2D6 in patients genotyped for CYP2D6 mutations
Human Psychopharmacol., year: 2000, volume: 2000, edition: 4
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Electrophysiological changes preceding voluntary movement in epileptic patients recorded with depth electrodes.
Homeostasis, year: 2000, volume: 40, edition: 3-4
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Event-related potentials and unilateral vagal nerve stimulation in epileptic patients.
European Journal of Neurology, year: 2000, volume: 7, edition: 3
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Experiential component of an emotional response induced by mental image of uncontrollable threat in healthy volunteers
Homeostasis, year: 2000, volume: 40, edition: 3-4