Project information
Motions in Disordered Proteins (MoDiPro)

Information

This project doesn't include Faculty of Economics and Administration. It includes Central European Institute of Technology. Official project website can be found on muni.cz.
Project Identification
12.251-Sciex-N-7
Project Period
6/2013 - 5/2014
Investor / Pogramme / Project type
Ostatní - foreign
MU Faculty or unit
Central European Institute of Technology
Cooperating Organization
École Polytechnique Fédérale de Lausanne

A research of intrinsically disordered proteins attract an increasing
attention because of their unclear role in biological processes and
diseases. The description of internal dynamics of intrinsically
disordered proteins is highly demanded as the attempt for a structural
determination is not relevant. A solution-NMR appears as the optimal
experimental technique for study of such proteins, because the possible
insight into the motion of molecules is one of major benefits of NMR.
Molecular motions at various timescales are usually studied by analyzing
experimental relaxation rates. The investigation of motions within the
unstructured, highly flexible parts of proteins is a challenging task,
because the assumptions required by a standard approaches are not
fulfilled.

Publications

Total number of publications: 1


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