Epidemiological of and risk factors for Alzheimers disease: a review

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Authors

POVOVÁ Jana AMBROŽ Petr BAR Michal PAVŮKOVÁ Veronika ŠERÝ Omar TOMÁŠKOVÁ Hana JANOUT Vladimír

Year of publication 2012
Type Article in Periodical
Magazine / Source Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic
MU Faculty or unit

Faculty of Science

Citation
Doi http://dx.doi.org/10.5507/bp.2012.055
Field Physiology
Keywords Alzheimers disease; epidemiology; risk factors; prevention
Description Based on epidemiological studies, genetic studies, neuroimaging methods and neuropathology research, three basic etiological hypotheses of the development of AD have been formulated: genetic, vascular and psychosocial. At present, the level of evidence is insufficient for the etiological role of other factors, such as nutrition, occupational exposure to various substances and inflammation. From the point of view of early diagnosis and application of primary or secondary prevention principles, genetic factors are the most important.
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