MicroRNAs and the Hallmarks of Cancer

Investor logo

Warning

This publication doesn't include Faculty of Economics and Administration. It includes Central European Institute of Technology. Official publication website can be found on muni.cz.
Authors

SLABÝ Ondřej

Year of publication 2012
Type Chapter of a book
MU Faculty or unit

Central European Institute of Technology

Citation
Description A growing amount of evidences proves that microRNAs (miRNAs) can work as oncogenes (activating the malignant potential) or tumor suppressor genes (blocking the malignant potential) and they can affect all of the six hallmarks of cancer defined by Hanahan and Weinberg (2000) as: self-sufficiency in growth signals, insensitivity to growth inhibitory signals, evasion of apoptosis, limitless replicative potential, sustained angiogenesis and tissue invasion and metastasis. In this chapter we focus on miRNAs significance in these various aspects of cancer biology.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.