Identification of MicroRNAs associated with early relapse after nephrectomy in renal cell carcinoma patients

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Authors	SLABÝ Ondřej RÉDOVÁ Martina POPRACH Alexandr NEKVINDOVÁ Jana ILIEV Robert RADOVÁ Lenka LAKOMÝ Radek SVOBODA Marek VYZULA Rostislav
Year of publication	2012
Type	Article in Periodical
Magazine / Source	Genes Chromosomes & Cancer
MU Faculty or unit	Central European Institute of Technology
Citation
Web	http://onlinelibrary.wiley.com/doi/10.1002/gcc.21957/pdf
Doi	http://dx.doi.org/10.1002/gcc.21957
Field	Oncology and hematology
Keywords	microRNA; renal cell carcinoma; relaps; nephrectomy
Description	Renal cell carcinoma (RCC) is the most common neoplasm of adult kidney. One of the important unmet medical needs in RCC is prognostic biomarker enabling identification of patients at high risk of relapse after nephrectomy. MicroRNAs (miRNAs) constitute a robust regulatory network with posttranscriptional regulatory efficiency for almost one-half of human coding genes, including oncogenes and tumor suppressors.
Related projects:	CEITEC - Central European Institute of Technology