Nové postupy v antikoagulační léčbě u seniorů s fibrilací síní

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Title in English New approaches in anticoagulant therapy in elderly patients with atrial fibrillation
Authors

ŠPÁC Jiří KIANIČKA Bohuslav

Year of publication 2012
Type Article in Periodical
Magazine / Source Kardiologická revue
MU Faculty or unit

Faculty of Medicine

Citation
Field Cardiovascular diseases incl. cardiosurgery
Keywords anticoagulation treatment; atrial fibrillation; warfarin; gatrans; xabans
Description New approaches to anticoagulant treatment for senior citizens with atrial fibrillation. Anticoagulant treatment for senior citizens with atrial fibrillation represents one of the most frequently administered treatments, with a relatively safe risk profile. Before beginning the procedure, it is necessary to carry out a risk assessment to assist the selection of a suitable therapy and in assessment of the risk of side-effects (bleeding). Until recently, the only anticoagulant was warfarin, which has a number of shortcomings. In recent years, a number of anticoagulant substances have appeared that block the functioning of thrombin or factor X, and which have shown in a number of clinical tests greater effectiveness in the prevenbon of thromboses connected to lower prevalence of bleeding. New anticoagulants have not only a number of advantages, but also some limitations that must be respected during treatment so that the benefits of new substances are not negated through incorrect use in practice.
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