Association of eNOS gene polymorphisms T-786C and G894T with blood pressure variability in man

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Authors

JÍRA Miroslav ZÁVODNÁ Eva HONZÍKOVÁ Nataša NOVÁKOVÁ Zuzana VAŠKŮ Anna IZAKOVIČOVÁ HOLLÁ Lydie FIŠER Bohumil

Year of publication 2011
Type Article in Periodical
Magazine / Source Physiological Research
MU Faculty or unit

Faculty of Medicine

Citation
Web http://www.biomed.cas.cz/physiolres/pdf/60/60_193.pdf
Field Physiology
Keywords Arterial blood pressure variability; Spectral analysis; Nitric oxide synthase; Genetics; Polymorphism
Description The aim of this study was to evaluate the association of polymorphisms T-786C and G894T in the gene encoding eNOS with blood pressure variability (BPV) in man. In conclusion, the haplotype formed by less frequent alleles of both eNOS variants was associated with increased systolic and diastolic BPV in this study.
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