Mutagenesis of Lectin PA-IIL from Pseudomonas aeruginosa as a Tool for Preparation of Lectins with Tune Specificity and Affinity
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| Year of publication | 2010 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | Carbohydrate-mediated recognition plays an important role in the ability of pathogenic bacteria to adhere to the surface of the host cell in the first step of their invasion and infectivity. A saturated mutagenesis of the specificity binding loop of PA-IIL lectin in silico was performed and selected mutants have been studied in vitro. |
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