Úloha stereotaktické biopsie v diagnostice tumoru mozku

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Title in English The role of stereotactic biopsy in brain tumor diagnostics
Authors

CHRASTINA Jan NOVÁK Zdeněk JANČÁLEK Radim ŘÍHA Ivo SLANÁ Bronislava HERMANOVÁ Markéta FEITOVÁ Věra

Year of publication 2011
Type Article in Periodical
Magazine / Source Onkologie
MU Faculty or unit

Faculty of Medicine

Citation
Field Neurology, neurosurgery, neurosciences
Keywords brain tumors; Stereotaxy; Frameless technique; Biopsy
Description Histological verification is a prerequisite for adequate therapy of brain tumors. Study presents the experience with stereotactic biopsy of brain tumors paying attention to diagnostic utility, correlation of findings with tumor resection and surgical safety. Brain tumor biopsy using stereotactic frame based system (deep and small lesions) was performed in 106 patients and frameless neuronavigation system BrainLab (superficially located lesions) was used in 20 patients. Diagnostic efficiency was 96.3 % in frame based system and 100% in frameless system. The incidence of complications was 1,8 % in frame based biopsies. There was one asymptomatic haematoma in frameless biopsy patients. Suspected brain tumor was not proven in 12.8 % of patient. There was correlation of histological findings in specimens taken during stereotactic biopsy and open tumor resection (10 patients) in all except one patient (malignant glioma grading). Frameless and neuronavigation based tumor biopsy is a safe procedure beneficial for the treatment of brain tumor patiens. The decision about the use of frame based or frameless system depends on lesion location (frame based system in deep lesions), lesion extent (frameless system in extensive subcortical tumors) and planned treatment steps.
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