125I-labelled iodothyronines: Useful tools for studies of effects of an antidepressant drug fluoxetine in the rat

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Authors

PAVELKA Stanislav

Year of publication 2010
Type Article in Periodical
Magazine / Source Chemické Listy
MU Faculty or unit

Faculty of Science

Citation
Field Biochemistry
Keywords Enzyme; radiometric determinations; iodothyronine deiodinases
Description With the use of adapted radiometric enzyme assays for iodothyronine sulfotransferases and uridine 5’-diphospho-glucuronyltransferase, as well as of our newly developed radiometric assays for iodothyronine deiodinases of types 1, 2 and 3, we studied the interaction of an antidepressant drug Fluoxetine with the metabolism of thyroid hormones in the rat.
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