Allenyloxime - A New Versatile Precursor for the Synthesis of Heterocycles
| Authors | |
|---|---|
| Year of publication | 2010 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | We have developed a new methodology for synthesis of diverse heterocyclic compounds based on a simple starting material. Selected allenyloximes shoved high reactivity toward heterocyclizations when exposed to different reaction conditions. Cyclic nitrones bearing various functional groups at positions 2 and 5 were generated. Obtained products were isolated, fully characterized or served as key intermediates for further modification of nitrone skeleton in effective one-pot domino reactions. Additionally, a chemistry of selected cyclic products was explored. Prepared nitrones underwent 1,3-dipolar cycloadditions and with several reactive dipolarophiles formed corresponding products. |
| Related projects: |