Vang-like protein 2 and Rac 1 interact to regulate adherens junctions

Lindqvist, Maria; Horn, Zachi; Bryja,  Vítězslav; Schulte,  Gunnar; Papachristou, Panagiotis; Ajima, Rieko; Dyberg, Cecilia; Arenas, Ernest; Yamaguchi, Terry P; Lagercrantz, Hugo; Ringstedt, Thomas

Vang-like protein 2 and Rac 1 interact to regulate adherens junctions

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Authors	LINDQVIST Maria HORN Zachi BRYJA Vítězslav SCHULTE Gunnar PAPACHRISTOU Panagiotis AJIMA Rieko DYBERG Cecilia ARENAS Ernest YAMAGUCHI Terry P LAGERCRANTZ Hugo RINGSTEDT Thomas
Year of publication	2010
Type	Article in Periodical
Magazine / Source	JOURNAL OF CELL SCIENCE
MU Faculty or unit	Faculty of Science
Citation
Field	Genetics and molecular biology
Keywords	Cell adhesion; Neurulation; PCP; Wnt
Description	The Wnt Planar Cell Polarity (PCP) pathway signals through small Rho-like GTPases to regulate the cytoskeleton. Here we investigate the function of the mammalian PCP protein Vangl2. We propose that Vangl2 affects cell adhesion and the cytoskeleton by recruiting Rac1 .
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