Base pair stacking in nucleosome DNA and bendability sequence pattern

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Authors

TRIFONOV Eduard

Year of publication 2009
Type Article in Periodical
Magazine / Source Journal of Theoretical Biology
MU Faculty or unit

Faculty of Science

Citation
Field Genetics and molecular biology
Keywords Chromatin; Chromatin code; DNA deformation; DNA minor grooves; Nucleosome DNA sequence; Nucleosome positioning
Description DNA deformation in the nucleosome involves partial unstacking between bases and base pairs. By adjusting orientations of different base-pair stacks relative to the histone octamer surface, the optimal set of stacks and their positions is derived, resulting in a sequence pattern best suitable for nucleosome DNA.
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