Modulation of steroidogenesis by coastal waters and sewage effluents of Hong Kong, China, using the H295R assay

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Authors	GRACIA T. JONES P.D. HIGLEY E.B. HILSCHEROVÁ Klára NEWSTED J. MURPHY M.B. CHAN A.K.Y. ZHANG X.W. HECKER M. LAM P.K.S. WU R.S.S. GIESY J.P.
Year of publication	2008
Type	Article in Periodical
Magazine / Source	Environmental Science and Pollution Research
MU Faculty or unit	Faculty of Science
Citation
Field	Environment influence on health
Keywords	H295R; endocrine disruption; in vitro
Description	This complex study investigates modulation of steroidogenesis in model adrenocortical cell line H295R by samples from coastal waters and sewage effluents of Hong Kong. It shows significant modulations of several steroidogenic enzymes by the tested environmental samples.
Related projects:	Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL) New molecular biology and biochemical methods to monitor estrogens and other endocrine disruptors in the environment of the C.R.