Sarkom z interdigitujících dendritických buněk dolní končetiny rezistentní k vysokodávkované chemoterapii BEAM s autologní transplantací kmenových krvetvorných buněk - popis případu a přehled literatury

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Title in English Interdigitating dendritic cell sarcoma of low extremitis resistant to high dose chemotherapy BEAM with peripheral blood stem cell transplantation
Authors

ADAM Zdeněk VESELÝ Karel KREJČÍ Marta POUR Luděk FAKAN F. SOUMAROVÁ Renata NEUBAUER Jiří VANÍČEK Jiří ČERNÝ J. KŘEN L. BOLCÁK K. ŠMARDOVÁ Lenka HÁJEK Roman MAYER Jiří

Year of publication 2009
Type Article in Periodical
Magazine / Source Vnitřní lékařství
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords stem cell; transplantation; sarcoma
Description Interdigitating dendritic cell sarcoma is a rare neoplasm forming part of the group of malignancies derived from histocytic cell line. This osological unit can be detected only by special immunohistochemical exams.To our knowledge, the above description is the first documented case of interdigitating dendritic cell sarcoma located in the tibia and crus soft tissue. We have not found any description of high-dose therapy supported by autologous transplantation of blood-forming tissue for this type of tumour in relevant literature. In this case, we record chemoresistance to high-dose chemotherapy and certain radiosensitivty of the tumour at the same time.
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