Význam cytogenetických změn u relabujících pacientů s mnohočetným myelomem léčených novými typy léků

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Title in English The Impact of Cytogenetic abnormalities in relapsing multiple myeloma patients treated by new types of drugs
Authors

ZAORALOVÁ Romana KUGLÍK Petr VRANOVÁ Vladimíra OLTOVÁ Alexandra POUR Luděk KŘIVANOVÁ Andrea KREJČÍ Marta ADAM Zdeněk HÁJEK Roman

Year of publication 2008
Type Article in Periodical
Magazine / Source Klinická onkologie, Supplementum
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords Multiple myeloma; cytogenetics; FISH; Velcade; Thalidomid
Description In this paper we show an example of use the detection of chromosomal abnormalities (deletion 13q14, translocation t(4;14), deletion 17q13 and gain 1q21) using modified fluorescence in situ hybridization (FISH) and following searching for the impact of chromosomal abnormalities to succesful treatment of multiple myeloma patients.
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