Biologické zkoušky ß- slitin pro implantologii

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Title in English Biological tests of B-alloys for implantology
Authors

FILIPI Vladimír BŘEZINA Vítězslav

Year of publication 2008
Type Article in Proceedings
Conference Mezinárodní seminář SVC
MU Faculty or unit

Faculty of Medicine

Citation
Field Other medical specializations
Keywords ß-alloy; biological tests; biocompatibility; adhesion
Description Aim of study: For a period of 12 months, in the Research Centre of Stomatology, we had been studying adhesion of cells to alloys of Ti Ta, Ti Al Fe, Ti Al V, Ti Nb, and Ti Mo in laboratory conditions. Material and methods:In each sample, adhesion to both quickly and slowly cooled alloys was compared by means of an electron microscope. SEM: treatment of cellular material on tested ssmples from Ti alloys. Samples on discs of 3x8 mm are cleaned and sterilised in an autoclave, then put into culture dishes under sterile conditions. Test cells: HeLa cell lines, culture medium: MEM + 5% NCS with the addition of L-glutamine and antibiotics with antimycotics. Conclusion: In the alloys of Ti Ta, Ti Al Fe, and Ti Al V studied, both adhesion and biocompatibility were comparable with the control group and the method of alloy cooling proved to be insignificant. The use of these new alloys in implantology seems to be very promising in future, and therefore further research appears desirable. The study is based on a Research Centre of Stomatology project of the Ministry of Education, Youth, and Sports of the Czech Republic, No. 1M0528.
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