C-Geranyl Compounds from <i>Paulownia tomentosa</i> Fruits
| Authors | |
|---|---|
| Year of publication | 2007 |
| Type | Article in Periodical |
| Magazine / Source | Journal of Natural Products |
| MU Faculty or unit | |
| Citation | |
| Web | DOI: 10.1021/np070063w |
| Doi | http://dx.doi.org/10.1021/np070063w |
| Field | Analytic chemistry |
| Keywords | flavonoid; geranyl; natural product; NMR |
| Description | Five geranylflavonoids, one prenylated flavonoid, and a simple flavanone were isolated from an ethanolic extract of Paulownia tomentosa fruit. Tomentodiplacol (1), 3-O-methyl-5-methoxydiplacol (2), 6-isopentenyl-3-O-methyltaxifolin (3), and dihydrotricin (4) are reported from a natural source for the first time and 3-O-methyldiplacone (6) for the first time from the genus Paulownia. The structures of the compounds were determined by mass spectrometry, including HR-MS, and by 1D and 2D NMR spectroscopy. The cytotoxicity and DPPH (2,2-diphenyl-1-picrylhydrazyl) quenching activity of some of these compounds were tested, with diplacone proving to be the best antioxidant, though the most cytotoxic compound. |
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