Cytotoxicity and Aryl Hydrocarbon Receptor-Mediated Activity of N-heterocyclic Polycyclic Aromatic Hydrocarbons - Structure-Activity Relationships.

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Authors

SOVADINOVÁ Iva BLÁHA Luděk JANOŠEK Jaroslav HILSCHEROVÁ Klára GIESY J. JONES P.D. HOLOUBEK Ivan

Year of publication 2006
Type Article in Periodical
Magazine / Source Environmental Toxicology and Chemistry
MU Faculty or unit

Faculty of Science

Citation
Field Environment influence on health
Keywords Cytotoxicity;Aromatic Hydrocarbons
Description This study presents results of cytotoxicity and Aryl Hydrocarbon Receptor-Mediated Activity of N-heterocyclic Polycyclic Aromatic Hydrocarbons along with their parental compounds determined in a model in vitro system. Structure-Activity Relationship was performed to determine the structural features of the compounds related to the observed effects.
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