Changes in diffusion parameters, energy-related metabolites and glutamate in the rat cortex after transient hypoxia/ischemia

Homola, Aleš; Zoremba, Norbert; Šlais,  Karel; Kuhlen, Ralf; Syková, Eva

Changes in diffusion parameters, energy-related metabolites and glutamate in the rat cortex after transient hypoxia/ischemia

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Authors	HOMOLA Aleš ZOREMBA Norbert ŠLAIS Karel KUHLEN Ralf SYKOVÁ Eva
Year of publication	2006
Type	Article in Periodical
Magazine / Source	Neuroscience Letters
MU Faculty or unit	Faculty of Medicine
Citation
Field	Pharmacology and pharmaceutical chemistry
Keywords	Hypoxia; Extracellular space; Microdialysis; Ischemia; Diffusion
Description	In this study we investigated how changes in ECS volume and geometry in the rat somatosensory cortex during and after transient hypoxia/ischemia correlate with extracellular concentrations of energy-related metabolites and glutamate.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.