Novinky v léčbě bipolární deprese

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Title in English New treatment possibilities for bipolar depression
Authors

ČEŠKOVÁ Eva

Year of publication 2006
Type Article in Periodical
Magazine / Source Psychiatrie pro praxi
MU Faculty or unit

Faculty of Medicine

Citation
Field Psychiatry, sexuology
Keywords bipolar depression; the 2nd generation of antipsychotics; quetiapine; olanzapine
Description At first general principles of treatment of bipolar disorder are summarized. Further the paper is dealing with the treatment of bipolar depression. In this indication the treatment with atypical antipsychotics is becoming a point of interest. Recently, two double-blind, randomized placebo-controlled studies in patients with bipolar depression comparing olanzapine and combination of olanzapine and fluoxetine with placebo and quetiapine with placebo were published. Quetiapine monotherapy at doses of 300 and 600 mg pro die demonstrated stapared with placebo from week 1 onward and was well tolerated.
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