Gender differences in cannabinoid and ecstasy interacting effects in mice
| Authors | |
|---|---|
| Year of publication | 2006 |
| Type | Article in Periodical |
| Magazine / Source | Homeostasis in Health and Diseases |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | Gender differences; ecstasy; open field; cannabinnoid |
| Description | The present experiment was focused on a possible cross-sensitization to ecstasy with repeated application of cannabinoid CB1 receptor ligands with (agonist methanandamide) or without (AM 251) intrinsic activity. We also have considered possible gender differences which other authors had described in behavioural effects of ecstasy in mice. Evaluation of behavioural sensitization was based on changes of drug effects on mouse locomotor activity in the open field test measured by the device Actitrack. Both, male and female mice of the same age were used. |
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