Genomová hybridizace kmenů T. pallidum Nichols a SS14 na oligonukleotidovém čipu

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Title in English Genome hybridizations of T. pallidum strains Nichols and SS14 on the oligonucleotide array
Authors

MATĚJKOVÁ Petra ŠMAJS David

Year of publication 2005
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description The genome of Treponema pallidum ssp. pallidum strain SS14, the causative agent of syphilis, was sequenced using oligonucleotide arrays. The sequences of more than 49 kb of the SS14 genome were verified by capillary sequencing approach. When compared to T. pallidum ssp. pallidum strain Nichols, the genome of SS14 contained 329 single nucleotide changes (219 transitions and 104 transversions), 7 deletions and 4 insertions.
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