NMR of Nucleic Acids

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Authors

FIALA Radovan ZERBE Oliver SKLENÁŘ Vladimír

Year of publication 2002
Type Chapter of a book
MU Faculty or unit

Faculty of Science

Citation
Description The paper concentrates primarily on the recent development of the high-resolution NMR techniques that have shown potential of increasing the range of promising applications and capability to provide new structural information. These include the 2H, 13C, and 15N isotope-labeling techniques for RNA and DNA, sensitivity optimized multi-dimensional NMR experiments, techniques to detect hydrogen-bond networks, applications of residual dipolar couplings for extracting structural restrains, and relaxation studies providing the information on dynamics and structure.
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