Vztah mezi EM a PM CYP 2D6 ve výskytu sexuálních dysfunkcí

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Title in English	The relation between EM and PM CYP 2D6 in sexual dysfunction
Authors	ŽOURKOVÁ Alexandra HADAŠOVÁ Eva ROBEŠ Miroslav
Year of publication	2001
Type	Article in Periodical
Magazine / Source	Psychiatrie
MU Faculty or unit	Faculty of Medicine
Citation
Field	Psychiatry, sexuology
Keywords	sexual dysfunctions; paroxetine; CYP 2D6; poor metabolizer; extenzive metabolizer
Description	The paper deals with th incidence of sexual dysfunction in treatment by paroxetine depending on CYP 2D6 activity. The group of 20 patients included 14 with sexual dysfunction. The statistic comparison (by the Mann-Whitney test) of ASEX UKU and SFM/SFŽ scale items revealed a statistic significant women with recuded CYP 2D6 metabolic capacity in the lubrical on, sexual desire, and self-evaluation items.
Related projects:	Plasticity of Regulatory Mechanisms of the Central Nervous Systems