Změny závislosti na metamfetaminu u potkanů vlivem serotonergik a kanabinoidů

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Title in English	Changes of methamphetamine dependence in rats caused by serotonergics and cannabinoids
Authors	NOVÁKOVÁ Jana VINKLEROVÁ Jana
Year of publication	2000
Type	Article in Proceedings
Conference	Abstrakta - 44. Studentská vědecká konference, LF MU Brno, 17. 5. 2000
MU Faculty or unit	Faculty of Medicine
Citation
Field	Pharmacology and pharmaceutical chemistry
Description	Changes of methamphetamine intake followed the pretreatment with serotonergics and cannabinoids were studied in the model "i.v. drug self-administration" in rats. The exogenous facilitation of neurotransmitter functions of serotonin (e.g. by fluoxetine) in the brain supressed the intake of drug. The incresed intake of methamphetamine was observed after the pretreatment with the cannabinoid agonists, on the contrary the cannabinoid antagonist caused the opposite effect.
Related projects:	Plasticity of Regulatory Mechanisms of the Central Nervous Systems