CCL2/MCP-1, interleukin-8, and fractalkine/CXC3CL1: Potential biomarkers of epileptogenesis and pharmacoresistance in childhood epilepsy

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Authors

ČESKÁ Katarína PAPEŽ Jan OŠLEJŠKOVÁ Hana SLABÝ Ondřej RADOVÁ Lenka LOJA Tomáš LIBÁ zuzana SVĚRÁKOVÁ Anna BRÁZDIL Milan AULICKÁ Štefánia

Year of publication 2023
Type Article in Periodical
Magazine / Source EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.sciencedirect.com/science/article/pii/S1090379823000910?via%3Dihub
Doi http://dx.doi.org/10.1016/j.ejpn.2023.06.001
Keywords Chemokine; Cytokine; Epileptogenesis; Interleukin; Pharmacodependent; Pharmacoresistant.
Attached files
Description Confirmation of the theory that IL-8 is generated from glial cells or astrocytes, not by leakage from plasma. • New insights into processes of epileptogenesis and development of pharmacoresistance in epilepsy with potential impact on developing disease-modifying drugs in epilepsy.
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