Effects of novel hydroxamic acids on cell cycle progression and cytodifferentiation
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| Year of publication | 2022 |
| Type | Appeared in Conference without Proceedings |
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| Description | At the Department of Chemical Drugs of the Pharmaceutical Faculty, Masaryk University, a new group of hydroxamic acids was designed and synthesized based on similarity to the structure of vorinostat. The aim of the project was to evaluate the effects of selected new hydroxamic acids on the processes of cell cycle progression and cytodifferentiation in the monocytic leukemia cell line and to compare these effects with the activity of a reference substance, vorinostat. |
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