Insights into the binding of the drugs to human serum albumin: capillary electrophoretic and calorimetry approaches

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Authors

MICHALCOVÁ Lenka GLATZ Zdeněk NEVÍDALOVÁ Hana

Year of publication 2015
Type Conference abstract
MU Faculty or unit

Faculty of Science

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Description The aim of this contribution was to present results of measurement of binding constant using two different methods: capillary electrophoresis - frontal analysis (CE-FA) and isothermal titration calorimetry (ITC). These methods were used to determine the binding parameters, such as constants and number of binding sites, of the model systems (albumin - drugs). These results were compared.
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