Dihydropyrrolo[1,2-b]pyrazoles. Synthesis of New Derivatives and Their Biological Evaluation

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Authors

TENORA Lukáš GALETA Juraj KRYŠTOF Vladimír POTÁČEK Milan

Year of publication 2014
Type Conference abstract
MU Faculty or unit

Faculty of Science

Citation
Description We present here our recent work aimed at the synthesis of some analogues with dihydropyrrolo[1,2-b]pyrazole (DPP) core bearing 2-pyridyl, 4-pyridyl and 4-quinolinyl moiety at position 2. Homoallenyl aldehyde is a key intermediate for the creation of DPP core. Various palladium catalyzed coupling reactions (Suzuki, Sonogashira, Heck, direct arylation and C-H activation) are shown in this work.
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