Germinom thalamu u dítěte s projevy předčasné pseudopuberty - kazuistika

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Title in English	Thalamic germinoma in a child with symptoms of precocious pseudopuberty - A case report
Authors	PAVELKA Zdeněk MAGNOVÁ Olga KŘEN Leoš SVOBODA Tomáš BRICHTOVÁ Eva ŠTĚRBA Jaroslav
Year of publication	2013
Type	Article in Periodical
Magazine / Source	Česká a Slovenská neurologie a neurochirurgie
MU Faculty or unit	Faculty of Medicine
Citation
Web	http://www.lexum.cz/o-ocni-klinice-lexum/news/oftalmologove-z-jiznich-cech-na-seminari-kliniky-lexum
Field	Neurology, neurosurgery, neurosciences
Keywords	Central nervous system; Chemotherapy; Germinoma; Human chorionic gonadotropin; Pseudopuberty; Radiotherapy
Description	We describe a case of a 6 years old boy with germinoma of an unusual thalamic localization that presented with precocious pseudopuberty based on ectopic human chorionic gonadotropin (hCG) secretion. The tumour was confirmed with stereotactic biopsy; subsequent chemotherapy and radiotherapy led to complete remission. The mechanism of precocious pseudopuberty and clinical and treatment aspects of brain germinomas in children are discussed.